Antioxidant, analgesic and anti-inflammatory activities of the methanolic extract of Piper betle leaves
نویسندگان
چکیده مقاله:
Objective:The present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of Piper betle leaves (MPBL). Materials and Methods: MPBL was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. Analgesic activity of MPBL was evaluated by hot plate, writhing, and formalin tests. Total phenolic and flavonoids content, total antioxidant activity, scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, peroxynitrate (ONOO-) as well as inhibition of total ROS generation, and assessment of reducing power were used to evaluate antioxidant potential of MPBL. Results: The extract of MPBL, at the dose of 100 and 200 mg/kg, produced a significant (p
منابع مشابه
antioxidant, analgesic and anti-inflammatory activities of the methanolic extract of piper betle leaves
objective:the present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of piper betle leaves (mpbl). materials and methods: mpbl was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. analgesic activity of mpbl was evaluated by hot plate, writhing, and formalin tests. total phenolic and fla...
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عنوان ژورنال
دوره 3 شماره 2
صفحات 112- 125
تاریخ انتشار 2013-03-01
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